• The data also revealed notable differences in

  2019-06-06

  

  The data also revealed notable differences in practice patterns across the countries. In France, Italy, Spain and the UK, patients were most likely to have multiple disseminated sites of metastases at the time of initial bone kanamycin detection; however, patients in Germany were most likely to hav

• El t tulo del poema

  2019-06-06

  

  El título del poema define una intertextualidad que se refuerza tipográficamente por medio de las cursivas del primer verso. La diferencia gráfica entre las palabras que integran este verso resalta el signo de la negación —el adverbio “no”— expresando una contradicción que culmina en los dos versos

• O processo de sele o

  2019-06-06

  

  O processo de seleção é crucial, pois ache inhibitor ‘escolhida’ será a responsável, nos próximos cinco anos, pela gestão do hospital determinado, decisão publicada em Diário Oficial. Dois aspectos são merecedores de atenção. Inicialmente, a decisão unilateral de escolha pelo Secretário de Saúde por

• La relaci n entre el narcotr

  2019-06-06

  

  La relación entre el narcotráfico y los grupos guerrilleros y los paramilitares se ha dado: “[…] no sólo como fuente de financiación sino como actor con intereses propios, ya que han aumentado significativamente las ‘familias’ que se dedican al tráfico de drogas, que a su vez están aumentando sus fo

• RANK RANKL The RANK RANKL signaling pathway is

  2019-06-05

  

  RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e

• Solamargine br As the only methods available for dual protec

  2019-06-05

  

  As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this Sol

• On what might an argument for

  2019-06-05

  

  On what might an argument for a fairer distribution of malaria research investment rest? The investments analysed by Head and colleagues were those made from outside of sub-Saharan Africa, not by African countries themselves, and were a mix of public funds channelled through bilateral and multilater

• In patients with systolic heart

  2019-06-05

  

  In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all histone methyltransferase of heart f

• A year old male was referred to our hospital

  2019-06-05

  

  A 59-year-old male was referred to our hospital in cardiogenic shock. A 12-lead electrocardiogram showed abnormal Q-waves in V1–V4 leads and complete atrioventricular block; the patient was diagnosed with acute myocardial infarction (AMI) (Fig. 1). Upon arrival, the patient was unconscious, and his

• br Discussion and outstanding questions Reproductive endocri

  2019-06-05

  

  Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa

• Despite the challenges since the Safe Motherhood Initiative

  2019-06-01

  

  Despite the challenges, since the Safe Motherhood Initiative was launched almost 30 years ago, international institutions such as the World Bank and WHO, and independent groups such as the Institute for Health Metrics and Evaluation, have developed, published, and continually refined estimates of ma

• The presence of an inflammatory

  2019-06-01

  

  The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha

• br Introduction Liver fibrosis cirrhosis is a global health

  2019-06-01

  

  Introduction Liver fibrosis/cirrhosis is a global health problem that leads to morbidity and mortality. Alcohol abuse is one of the most common causes of liver fibrosis/cirrhosis in western developed countries and accounts for more than 50% of cirrhosis cases. Alcoholic liver fibrosis is characte

• Of indicators in the Index ten

  2019-06-01

  

  Of 101 indicators in the Index, ten fulfilled all comparability criteria for the detailed longitudinal analysis, and six core-scored indicators with the highest correlation with overall scores were used for the detailed longitudinal analysis. We made several important observations. First, the crude

• Por ltimo una divergencia crucial entre los bestiarios

  2019-06-01

  

  Por último, una divergencia crucial entre los bestiarios y las historias naturales está en la característica glosa alegórica que condujo la lectura moral de la 5 aza 2 deoxycytidine en el Bestiario; en la historia natural primó una lectura literal o “histórica” que se finca en la experiencia de los

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