• br Unacceptably high rates of adverse outcomes persist for

  2019-05-08

  

  Unacceptably high rates of adverse outcomes persist for childbearing women and infants, including maternal and newborn mortality, stillbirth, and short-term and long-term morbidity. In light of the challenges to achieve the UN Sustainable Development Goals, it is timely to reconsider priorities fo

• methane monooxygenase Although the study is of

  2019-05-08

  

  Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show

• Both stunting and environmental enteric

  2019-05-08

  

  Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as Tenovin-6 or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these three Gambia

• Non communicable disease behavioural risk

  2019-05-08

  

  Non-communicable disease behavioural risk factors such as tobacco smoking, heavy alcohol consumption, physical inactivity, and unhealthy eating are socially patterned in high-income countries, with individuals of low socioeconomic status generally experiencing a higher burden of risk factors. Howeve

• In September a high level

  2019-05-07

  

  In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal

• Interpretation The SMART course can give orthopaedic surgeon

  2019-05-07

  

  Interpretation The SMART course can give orthopaedic surgeons practising in LMICs the skills and knowledge to successfully perform flaps and reduce amputation. While this reverse transcriptase inhibitors course offers a collaborative, sustainable approach to reduce global surgery disparities in amp

• mst2 br On March the Indian

  2019-05-07

  

  On March 10, 2016, the Indian Government banned around 330 “irrational” fixed-dose combination drugs (FDCs) with immediate effect. FDCs are products that mst2 contain two or more active drugs in a fixed-dose ratio, and are useful for minimising pill burden and lowering cost. However, FDCs should

• SAR405 br Other drugs Overdose of diphenhydramine an H

  2019-05-07

  

  Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium SAR405 and thus to unmask a BrS phenotype [60]. Alcohol

• Numerous clinical trials phase II and phase

  2019-05-07

  

  Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M

• br Conflict of interest br Introduction Bladder cancer is

  2019-05-07

  

  Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of Adriamycin cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men and in the elderly popula

• br Materials and methods br Results br Discussion

  2019-05-07

  

  Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential 3X FLAG tag (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4]. Howeve

• Introduction Osteosarcoma OS is the most commonly diagnosed

  2019-05-06

  

  Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple thera

• br Material and methods br Results br Discussion

  2019-05-06

  

  Material and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Matching the morphology of paced complexes to tachycardia complexes is useful for mapping arrhythmias. In the atrium, pace mapping is useful for focal atrial arrhythmias in orde

• br Mechanisms of arrhythmias Several schemes

  2019-05-06

  

  Mechanisms of arrhythmias Several schemes have been used to classify the mechanisms of cardiac arrhythmias. Traditionally, these have been divided into nonreentrant and reentrant activity [11]. An alternative scheme divided them into those occurring at the cellular and tissue levels [12]. A dynam

• In vitro test for EEC JAK mutations

  2019-05-06

  

  In vitro test for EEC, JAK2 mutations and paraclinical parameters were performed by routine analysis. Discussion It is always important to make the correct diagnosis – in particular when molecular biological analyses are available. The pursuit of the correct diagnosis was intensified in these b

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